Setup your smoker for indirect heat at 215°F. You can set it up higher or lower, depending on your smoker and how fast you want to smoke the pork butt. If I am smoking a pork butt overnight and I want it to finish in the afternoon, I will set the temperature to 200°F. If I am starting the cook in the morning and want to finish it around dinner time I will set the temperature to 275°F.
My favorite smoking woods for pork are oak, apple, cherry, and hickory. Pork takes almost any wood flavor on nicely, so feel free to experiment with wood flavors and combinations. My favorite is cherry and oak together.
For the best bark and flavor, I do not recommend wrapping the pork butt during any of the smoking. Just put it on and forget about it for at least 12 hours before checking on it.